PROCEDE POUR LA PREPARATION DES PHENYLALKYLAMINES
Compounds of the formula wherein R1 is hydrogen, -(CH2)n-R4 or -CO-R5, where N IS 1 OR 2, R4 is hydrogen, cyano or benzoyl, and R5 is hydrogen, lower alkoxy, benzyloxy, -CH2-NH2, -CH(CH3)-NH2, -CH2-NH-CH2-C6H5 or -CH(CH3)-NH-CH2-C6H5, R2 is hydrogen or methyl, and R3 is amino, nitro, -NH-CO-R6 or -N...
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Format: | Patent |
Sprache: | fre ; rum |
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Zusammenfassung: | Compounds of the formula wherein R1 is hydrogen, -(CH2)n-R4 or -CO-R5, where N IS 1 OR 2, R4 is hydrogen, cyano or benzoyl, and R5 is hydrogen, lower alkoxy, benzyloxy, -CH2-NH2, -CH(CH3)-NH2, -CH2-NH-CH2-C6H5 or -CH(CH3)-NH-CH2-C6H5, R2 is hydrogen or methyl, and R3 is amino, nitro, -NH-CO-R6 or -NH-A-R7, where R6 is hydrogen, methyl, methoxy, ethoxy, methylthio or ethylthio, R7 is amino, methylamino or dimethylamino, and A is -CO- or -SO2-, and non-toxic, pharmacologically acceptable acid addition salts thereof; the compounds as well as their salts are useful as hypertensives. |
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