FLUORESCENT 4-(4-(DIALKYLAMINO)BENZYLIDENE)-OXAZOL-5(4H)-ONE DERIVATIVES WITH BIOMEDICAL APPLICATIONS

The invention relates to compounds of the oxazol-5 (4H) -one class used as non-cytotoxic fluorescent agents for the detection and visualization of human tumor cells for diagnostic or therapy monitoring purposes. The claimed compounds are derived from 4- (4-( dialkylamino) benzylidene) oxazol-5(4H) -...

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Hauptverfasser:	NEAGOE IONELA VICTORIA, MANDA GINA, SURCEL MIHAELA, BĂRBUCEANU ŞTEFANIA-FELICIA, DRĂGHICI CONSTANTIN, NIŢULESCU GEORGE MIHAI, ROŞCA ELENA-VALENTINA, RUŢĂ LAVINIA LILIANA, ISCRULESCU LUCIAN, BĂRBUCEANU FLORICA, DINU PÎRVU CRISTINA ELENA, FĂRCĂŞANU ILEANA CORNELIA, APOSTOL THEODORA - VENERA
Format:	Patent
Sprache:	eng ; rum
Schlagworte:	ADHESIVES CHEMISTRY DYES HETEROCYCLIC COMPOUNDS MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FORELSEWHERE METALLURGY MISCELLANEOUS APPLICATIONS OF MATERIALS MISCELLANEOUS COMPOSITIONS NATURAL RESINS ORGANIC CHEMISTRY PAINTS POLISHES
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Beschreibung
Zusammenfassung:	The invention relates to compounds of the oxazol-5 (4H) -one class used as non-cytotoxic fluorescent agents for the detection and visualization of human tumor cells for diagnostic or therapy monitoring purposes. The claimed compounds are derived from 4- (4-( dialkylamino) benzylidene) oxazol-5(4H) -one containing an arylsulfonylphenyl moiety in position 2, of general formula I, wherein R is methyl or ethyl and X is H, Cl or Br.