PROCESS FOR PREPARING GD () COORDINATION COMPOUNDS CONTAINING AMPIROXICAM AND LORNOXICAM AS LIGANDS

The invention relates to a process for preparing Gd (III) coordination compounds containing ampiroxicam and lornoxicam as ligands. According to the invention, the process consists in bringing into contact an alcoholic solution containing oxicam with an aqueous solution containing Gd (III) chloride i...

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Bibliographische Detailangaben
Hauptverfasser:	PATRON LUMINIŢA ILEANA, RĂDULESCU FLAVIAN, ANDRIEŞ ADRIAN, MARINESCU GABRIELA, FALCOŞ MARIANA, NIŢĂ SULTANA, VINTILĂ MIHAELA, CULIŢĂ DANIELA CRISTINA, MOSCOVICI MIŞU, ALBULESCU RADU NICOLAE AUREL, DAMIAN ECATERINA
Format:	Patent
Sprache:	eng ; rum
Schlagworte:	CHEMISTRY COMPOUNDS OF THE METALS BERYLLIUM, MAGNESIUM, ALUMINIUM,CALCIUM, STRONTIUM, BARIUM, RADIUM, THORIUM, OR OF THERARE-EARTH METALS HUMAN NECESSITIES HYGIENE INORGANIC CHEMISTRY MEDICAL OR VETERINARY SCIENCE METALLURGY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The invention relates to a process for preparing Gd (III) coordination compounds containing ampiroxicam and lornoxicam as ligands. According to the invention, the process consists in bringing into contact an alcoholic solution containing oxicam with an aqueous solution containing Gd (III) chloride in a M:L molar ratio of 1:2, which, by refluxing, leads to the obtention of mononuclear coordination Gd (III) compounds. Invenţia se referă la un procedeu de obţinere a compuşilor coordinativi ai Gd(III), conţinând ca liganzi ampiroxicam şi lornoxicam. Procedeul conform invenţiei constă în aducerea în contact a unei soluţii alcoolice care conţine oxicam cu o soluţie apoasă care conţine clorură de Gd(III) în raport molar M:L de 1:2, care, prin refluxare, conduce la formarea compuşilor coordinativi mononucleari de Gd(III).