PROCESS FOR PREPARING COORDINATIVE COMPOUNDS OF CO(), CU(), ZN() HAVING MELOXICAM AS LIGAND

PROCESS FOR PREPARING COORDINATIVE COMPOUNDS OF CO(), CU(), ZN() HAVING MELOXICAM AS LIGAND

The present invention relates to a process for obtaining coordinative compounds of Co (II), Cu (II), Zn (II) used in therapy. According to the invention, the process consists in bringing in contact a methanol solution containing neutral/deprotonated meloxicam with an aqueous solution containing chlo...

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Bibliographische Detailangaben
Hauptverfasser: PATRON LUMINIŢA ILEANA, ANDRIEŞ ADRIAN, MARINESCU GABRIELA, FALCOŞ MARIANA, TĂNASE CRISTIANA, NIŢĂ SULTANA, VINTILĂ MIHAELA, ALBULESCU LUCIAN, CULIŢĂ DANIELA CRISTINA, RĂDULESCU FLAVIAN ŞTEFAN, ALBULESCU RADU NICOLAE AUREL, DAMIAN ECATERINA
Format: Patent
Sprache:eng ; rum
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The present invention relates to a process for obtaining coordinative compounds of Co (II), Cu (II), Zn (II) used in therapy. According to the invention, the process consists in bringing in contact a methanol solution containing neutral/deprotonated meloxicam with an aqueous solution containing chloride/acetate of Co (II), Cu (II) and Zn (II), respectively, in a molar ratio of 2 : 1, there being obtained coordinative compounds of Co (II), Cu (II) and Zn (II), respectively, where the metal ion has a distorted octahedral stereochemistry containing the water molecules in the axial positions.