PROCESSO PARA A PREPARACAO DE PIRAZOLO[4,3-D]PIRIMIDIN-7-ONAS E DE SEUS INTERMEDIARIOS

PROCESSO PARA A PREPARACAO DE PIRAZOLO[4,3-D]PIRIMIDIN-7-ONAS E DE SEUS INTERMEDIARIOS

A process is provided for the preparation of a compound of formulae (IA) (sidenafil/ ViagraTm TM ) and (IB) comprising reacting a compound of formula (IIA) and (IIB) respectively in the presence of OR, wherein R in the case of formation of compound (IA) is CH2CH3 and R in the case of formation of co...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: PETER JAMES DUNN, LEVETT, PHILIP CHARLES
Format: Patent
Sprache:por
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:A process is provided for the preparation of a compound of formulae (IA) (sidenafil/ ViagraTm TM ) and (IB) comprising reacting a compound of formula (IIA) and (IIB) respectively in the presence of OR, wherein R in the case of formation of compound (IA) is CH2CH3 and R in the case of formation of compound (IB) is CH2CH2CH3, where X is a leaving group: