PROCESSO PARA A PREPARACAO DE ANALOGOS DE OLIGONUCLEOTIDOS COM LIGACOES INTERNUCLEOTIDO 3'-3' OU 5'-5' TERMINAIS

Therapeutically utilisable oligonucleotides of the formulae I and II are obtained by introducing terminal 3'-3' or 5'-5' linkages. These nuclease-stable compounds suppress the biological function of nucleic acids.

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Bibliographische Detailangaben
Hauptverfasser: ANJA FROHLICH, HARTMUT SELIGER, HANNELORE ROSCH, MATTHIAS MONTENARH, JOSE FLAVIO RAMALHO-ORTIGAO
Format: Patent
Sprache:por
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Zusammenfassung:Therapeutically utilisable oligonucleotides of the formulae I and II are obtained by introducing terminal 3'-3' or 5'-5' linkages. These nuclease-stable compounds suppress the biological function of nucleic acids.