PROCESSO PARA A PREPARACAO E PURIFICACAO DE INTERLEUQUINA-3 HUMANA RECOMBINANTE DAS SUAS MUTEINAS E DE COMPOSICOES FARMACEUTICAS QUE AS CONTEM

Recombinantly produced IL-3 is purified in a series of steps, initially employing hydrophobic interaction, followed by ion-exchange chromatography and gel filtration. Furthermore methods are provided for improved production of recombinant hIL-3 either in glycosylated form from mammalian and yeast ce...

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Hauptverfasser: NICOLAAS LUDOVICUS, ROBERT WILLEM VAN LEEN, MARIA PERSOON
Format: Patent
Sprache:por
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Zusammenfassung:Recombinantly produced IL-3 is purified in a series of steps, initially employing hydrophobic interaction, followed by ion-exchange chromatography and gel filtration. Furthermore methods are provided for improved production of recombinant hIL-3 either in glycosylated form from mammalian and yeast cells or in unglycosylated form from prokaryotes.