PROCESSO PARA A PREPARACAO DE AGENTES DIURETICOS GLUTARAMIDA SUBSTITUIDA COM CICLOALQUILO

Compounds of formula (II), wherein each of R and R is independently H, C1-C6 alkyl, benzyl or an alternative biolabile ester-forming group; R is a C4 alkyl group; R is H, OH, C1-C4 alkyl or C1-C4 alkoxy; and R is defined to include a range of alkyl, alkenyl, alkynyl, arylalkynyl, cycloalkyl, cycloalkenyl, alkoxy, amino, substituted amino, amido, sulphonamido and substituted alkyl groups; and phamaceutically acceptable salts thereof, are diuretic agents of utility in the treatment of hypertension, heart failure, renal insufficiency and other disorders.