PROCESSO DE PREPARACAO DE ACIDOS CARBOXILICOS AZA-HETEROCICLICOS N-SUBSTITUIDOS E DE COMPOSICOES FARMACEUTICAS QUE OS CONTEM

Novel N-substituted azaheterocyclic carboxylic acids and esters thereof in which an ether group forms part of the N-substituent, the compounds thus having the general formula I wherein R and R are the same or different and each represents phenyl, 2-thienyl or 3-thienyl, 2-pyrrolyl or 3-pyrrolyl, substituted with one or more substituents selected among the following atoms or groups: hydrogen, halogen, C1-6-alkyl, C1-6-alkoxy or cyano; R and R each represents hydrogen or together represent a bond; m is 1 or 2 and n is 1 when m is 1 and n is 0 when m is 2; R and R each represents hydrogen or may - when m is 2 - together represent a bond, and R is OH or C1-8-alkoxy, p is 0 or 1 or 2, q is 0 or 1 or 2, R is H and C1-4-alkyl, are potent inhibitors of GABA uptake from the synaptic cleft.