PROCESSO PARA A PREPARACAO DE PEPTIDEOS INIBIDORES DE PROTEASES DO HIV, UTEIS PARA O TRATAMENTO DA SIDA
A therapeutic active compound, especially for treating AIDS, comprising (A min )k-(Z)n-(Y)m-A sec wherein A min is or hydrogen, wherein R is OR , NR R or CR R R , R ,R and R are, independent of each other, hydrogen, an aliphatic or an aromatic, wherein k is one or zero, wherein when Z is hydrogen, k...
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Format: | Patent |
Sprache: | por |
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Zusammenfassung: | A therapeutic active compound, especially for treating AIDS, comprising (A min )k-(Z)n-(Y)m-A sec wherein A min is or hydrogen, wherein R is OR , NR R or CR R R , R ,R and R are, independent of each other, hydrogen, an aliphatic or an aromatic, wherein k is one or zero, wherein when Z is hydrogen, k is zero, Z is hydrogen, Ser or Thr or R - @, wherein n is one or zero, with the proviso that when Y is hydrogen, n is zero, Y is hydrogen or R - @, or wherein R is hydrogen or an aliphatic or aromatic, wherein m is one or zero, wherein when E is hydrogen, m is zero, A sec is wherein E is hydrogen or Asn or R - @, wherein is a 4 to 7 membered ring system, wherein only Q, Q min , Q sec may be different from carbon, wherein the substituent is an aliphatic or aromatic, wherein E is @; wherein E is wherein E is wherein E is hydrogen or Asn, or but if E is R E is not R -O- @- , wherein R is an aromatic or aliphatic, wherein X is hydrogen or R or wherein R is an aliphatic, wherein R is hydrogen or wherein A has the formula |
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