LIGACAO DE ANTICORPOS A RECEPTORES (CCR2) DE PROTEINA 1 DE QUIMIO-ATRACCAO DE MONOCITOS (PQM-1)

The invention relates to antibodies which is capable of binding the monocyte chemoattractant protein 1 (MCP-1) receptor CCR2, especially those which are capable of acting either as an antagonist or agonist. The claimed antobodies can be used for in vitro and/or in vivo diagnostic, for screening and...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: JOSE MARIO MELLADO GARCIA, JOSE MIGUEL RODRIGUEZ FRADE, CARLOS MARTINEZ ALONSO, PETER LIND
Format: Patent
Sprache:por
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Beschreibung
Zusammenfassung:The invention relates to antibodies which is capable of binding the monocyte chemoattractant protein 1 (MCP-1) receptor CCR2, especially those which are capable of acting either as an antagonist or agonist. The claimed antobodies can be used for in vitro and/or in vivo diagnostic, for screening and detection of tissues and classes of cells expressing the MCP-1 receptor, for screening for new drugs and for therapeutic use. The invention also relates to a preparation comprising the claimed antibody and a micro-organism or cell-line capable of producing the claimed antibody.