PROCESSO DE PREPARACAO DE DERIVADOS DA QUINOLONA

A process to prepare compounds of formula I in which n = 0, 1 or 2 comprising the cyclisation of compounds of formula II in which n - 0, 1 or 2. The cyclisation may be effected in the presence of an organic or inorganic base or thermally at a temperature in the range 40-160 DEG C. Compounds of formu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	KENNETH JOHN NICHOL, KENNETH BARRON, DAVID LLOYD ROBERTS, LACHLAN MACLEAN
Format:	Patent
Sprache:	por
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	A process to prepare compounds of formula I in which n = 0, 1 or 2 comprising the cyclisation of compounds of formula II in which n - 0, 1 or 2. The cyclisation may be effected in the presence of an organic or inorganic base or thermally at a temperature in the range 40-160 DEG C. Compounds of formula II and certain analogues thereof are disclosed as cardiovascular agents.