METODO DE ISOLAMENTO DE INIBIDOR DO FACTOR DE TECIDO

A purified tissue factor inhibitor is provided which has the following characteristics: A. it exists in two forms, TFI1 migrating at about 37-40,000 daltons and TFI2 at about 25-26,000 daltons, as determined by sodium dodecylsulfate polyacrylamide gel electrophoresis, B. it has a partial N-terminal...

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Bibliographische Detailangaben
1. Verfasser:	GEORGE JOHN BROZE, JR
Format:	Patent
Sprache:	por
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	A purified tissue factor inhibitor is provided which has the following characteristics: A. it exists in two forms, TFI1 migrating at about 37-40,000 daltons and TFI2 at about 25-26,000 daltons, as determined by sodium dodecylsulfate polyacrylamide gel electrophoresis, B. it has a partial N-terminal amino acid sequence as follows: wherein X-X has not been determined, and C. it exhibits inhibitory activity to Factor Xa.