PROCESS FOR ISOLATE AND PURIFY CONCERNING A TISSUE PLASMINOGEN ACTIVATOR
A process for isolating tPA which comprises contacting a cell culture medium with a solid support onto which the tPA becomes adsorbed, washing the support with water buffered to < pH 5 and then eluting the tPA with an aqueous solution of an alkali or alkaline earth metal salt or a chaotrope buffe...
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| creator | ROBERT DAVID SITRIN SAMUEL GREGG FRANKLIN KYUNG OH JOHANSON JAMES EDWARD STRICKLER PATRICK JOSEPH MCDEVITT PETER ARLETTI DEPHILLIPS |
| description | A process for isolating tPA which comprises contacting a cell culture medium with a solid support onto which the tPA becomes adsorbed, washing the support with water buffered to < pH 5 and then eluting the tPA with an aqueous solution of an alkali or alkaline earth metal salt or a chaotrope buffered to < pH 5. |
| format | Patent |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
| title | PROCESS FOR ISOLATE AND PURIFY CONCERNING A TISSUE PLASMINOGEN ACTIVATOR |
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