FORMULACAO AQUOSA DE LIBERTACAO PROLONGADA COMPREENDENDO FACTOR DE LIBERTACAO DA HORMONA DO CRESCIMENTO BOVINO

Prolonged parenteral release into the circulatory system of a cow of a bioactive growth hormone releasing factor at desirably effective levels can be achieved using novel compositions in which the growth hormone releasing factor is present in an aqueous liquid at a dose of at least about 50 mg and a...

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Bibliographische Detailangaben
Hauptverfasser: TODD P. FOSTER, MICHAEL J. HAGEMAN, WILLIAM M. MOSELEY, JAMES F. CAPUTO
Format: Patent
Sprache:por
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Zusammenfassung:Prolonged parenteral release into the circulatory system of a cow of a bioactive growth hormone releasing factor at desirably effective levels can be achieved using novel compositions in which the growth hormone releasing factor is present in an aqueous liquid at a dose of at least about 50 mg and at a concentration of at least about 20 mg/ml. Preferably, the growth hormone releasing factor is present in an aqueous liquid at a dose of about 200 mg and at a concentration of about 180 mg/ml. The aqueous bovine growth hormone releasing factor formulation provides for the sustained release of bovine somatotropin into the circulatory system of the animal for greater than seven (7) days.