PROCESSO PARA A PREPARACAO DE DERIVADOS DE BENZO -3,4-DI-HIDRO-PIRIDINA E DE TIENO-3,4-DI-HIDRO-PIRIDINA E DE COMPOSICOES FARMACEUTICAS QUE OS CONTEM

PROCESSO PARA A PREPARACAO DE DERIVADOS DE BENZO -3,4-DI-HIDRO-PIRIDINA E DE TIENO-3,4-DI-HIDRO-PIRIDINA E DE COMPOSICOES FARMACEUTICAS QUE OS CONTEM

Benzo- and thieno-3,4-dihydropyridine derivatives of the formula I in which D denotes a group of the formula Ia or Ib and A and B denote a benzo or thieno radical; and R4 denotes (C1-C4)alkoxy or an -NR9R10 group in which R9 and R10 independently of one another denote (a) hydrogen, (b) branched or u...

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Hauptverfasser: ILSE STRELLER, FRANZ JOSEF KUHN, WALTER LOSEL, OTTO ROOS, DIETRICH ARNDTS, GEORG SPECK, GUNTHER SCHINQNITZ
Format: Patent
Sprache:por
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Benzo- and thieno-3,4-dihydropyridine derivatives of the formula I in which D denotes a group of the formula Ia or Ib and A and B denote a benzo or thieno radical; and R4 denotes (C1-C4)alkoxy or an -NR9R10 group in which R9 and R10 independently of one another denote (a) hydrogen, (b) branched or unbranched alkyl, alkenyl or alkynyl (where the alkyl can be substituted, for example by the group (c) cycloalkyl having 3-7 ring members, (d) dimethylamino, (e) amino(C2-C4)alkyl, (f) phenyl, (g) morpholinyl or (h) pyridinyl, or R9 and R10, together with the nitrogen atom to which they are bonded, denote a pyrrolidinyl, piperidinyl, morpholinyl or piperazinyl radical; and their pharmaceutically acceptable salts. The compounds have cardioprotective and/or cerebral protective action.