PROCESSO PARA A PREPARACAO DE LANOSTEROIS SUBSTITUIDOS NAS POSICOES 14 E 15 E DE COMPOSICOES HIPOCOLESTEROLEMICAS QUE OS CONTEM

PROCESSO PARA A PREPARACAO DE LANOSTEROIS SUBSTITUIDOS NAS POSICOES 14 E 15 E DE COMPOSICOES HIPOCOLESTEROLEMICAS QUE OS CONTEM

Lanosterols substituted in the 14 and/or 15 position(s) which are active in inhibiting lanosta-8,24-dien-3 beta -ol 14 alpha -methyl-demethylase activity, supressing 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGR) activity, decreasing cholesterol synthesis and reducing serum cholesterol level...

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Bibliographische Detailangaben
Hauptverfasser: JAMES MICHAEL TRZASKOS, ROBERT PAUL JOHNSON, RONALD LOUIS MAGOLDA, SOO SUNG KO, SIMON HENDRIK STAM
Format: Patent
Sprache:por
Schlagworte:
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
STEROIDS
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Beschreibung
Zusammenfassung:Lanosterols substituted in the 14 and/or 15 position(s) which are active in inhibiting lanosta-8,24-dien-3 beta -ol 14 alpha -methyl-demethylase activity, supressing 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGR) activity, decreasing cholesterol synthesis and reducing serum cholesterol levels are disclosed.