COMPOSICOES CONTENDO UMA PROTEINA MORFOGENETICA DO OSSO E UM FACTOR DE CRESCIMENTO DOS FIBROBLASTOS E METODOS PARA A INDUCAO DE CARDIOGENESE

A cardiogenic composition comprising a purified mixture of a transforming growth factor- beta protein and a fibroblast growth factor is disclosed. In another embodiment, the present invention is a method of inducing cardiogenesis in cells of a non-cardiac lineage comprising the steps of exposing cel...

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Bibliographische Detailangaben
Hauptverfasser: ZHU, XIAOLEI, JOHN E. BAKER, LOUGH, JOHN, W., JR, BROGLEY, MICHELE, A, BARRON, MATTHEW, R
Format: Patent
Sprache:por
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Zusammenfassung:A cardiogenic composition comprising a purified mixture of a transforming growth factor- beta protein and a fibroblast growth factor is disclosed. In another embodiment, the present invention is a method of inducing cardiogenesis in cells of a non-cardiac lineage comprising the steps of exposing cells to the composition and observing the development of cardiac cells.