PROCESS FOR PREPARING PHOSPHINO-HYDROCARBON-GROUP VIII-METAL COMPLEXES USEFUL AS ANTITUMOR AGENTS
Novel bis[bis(diphenylphosphino)hydrocarbon] and bis[diphenylphosphino-diphenylarsino)hydrcarbon]-group VIII metal compounds of the formula 1 of the formula sheet, whereinD, = D2 = phosphorus or D, = phosphorus and D2 = arsenic;A = (CH2)2 or cis-CH = CH;X, = X2 (both if present) = halo or nitrato or...
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creator | KLAAS TIMMER HARMEN ANNE MEINEMA |
description | Novel bis[bis(diphenylphosphino)hydrocarbon] and bis[diphenylphosphino-diphenylarsino)hydrcarbon]-group VIII metal compounds of the formula 1 of the formula sheet, whereinD, = D2 = phosphorus or D, = phosphorus and D2 = arsenic;A = (CH2)2 or cis-CH = CH;X, = X2 (both if present) = halo or nitrato or X, + X = peroxo;Y (if present) = halide, nitrate, perchlorate, triflate or tetrahaloferrate (III);n = 0, 1 or 2;M = Fe(II), Fe(III), Co(II), Rh(I), Rh(III), Ir(I), Ir(III), Ni(II) or Pd(II),showing a tumor cell growth-inhibiting activity, novel pharmaceutical compositions containing said compounds and a method for treating tumor cells, sensitive to said compounds. |
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CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1986</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19861101&DB=EPODOC&CC=PT&NR=83612A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19861101&DB=EPODOC&CC=PT&NR=83612A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KLAAS TIMMER</creatorcontrib><creatorcontrib>HARMEN ANNE MEINEMA</creatorcontrib><title>PROCESS FOR PREPARING PHOSPHINO-HYDROCARBON-GROUP VIII-METAL COMPLEXES USEFUL AS ANTITUMOR AGENTS</title><description>Novel bis[bis(diphenylphosphino)hydrocarbon] and bis[diphenylphosphino-diphenylarsino)hydrcarbon]-group VIII metal compounds of the formula 1 of the formula sheet, whereinD, = D2 = phosphorus or D, = phosphorus and D2 = arsenic;A = (CH2)2 or cis-CH = CH;X, = X2 (both if present) = halo or nitrato or X, + X = peroxo;Y (if present) = halide, nitrate, perchlorate, triflate or tetrahaloferrate (III);n = 0, 1 or 2;M = Fe(II), Fe(III), Co(II), Rh(I), Rh(III), Ir(I), Ir(III), Ni(II) or Pd(II),showing a tumor cell growth-inhibiting activity, novel pharmaceutical compositions containing said compounds and a method for treating tumor cells, sensitive to said compounds.</description><subject>ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM</subject><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1986</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqFjLEKwjAQQLs4iPoJwv1ABi2I61mvTaDNHblEdCpF4iRaqP-PHdyd3vAeb1kMErgiVag5gAQSDM43IJZVrPNs7O08FxhO7E0TOAlcnHOmo4gtVNxJS1dSSEp1agEV0EcXUzfvsCEfdV0sHsNzypsfV8W2plhZk8d3n6dxuOdX_vQSj-Vht8fyn_8ChbEy5A</recordid><startdate>19861101</startdate><enddate>19861101</enddate><creator>KLAAS TIMMER</creator><creator>HARMEN ANNE MEINEMA</creator><scope>EVB</scope></search><sort><creationdate>19861101</creationdate><title>PROCESS FOR PREPARING PHOSPHINO-HYDROCARBON-GROUP VIII-METAL COMPLEXES USEFUL AS ANTITUMOR AGENTS</title><author>KLAAS TIMMER ; HARMEN ANNE MEINEMA</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_PT83612A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1986</creationdate><topic>ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM</topic><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>KLAAS TIMMER</creatorcontrib><creatorcontrib>HARMEN ANNE MEINEMA</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>KLAAS TIMMER</au><au>HARMEN ANNE MEINEMA</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PROCESS FOR PREPARING PHOSPHINO-HYDROCARBON-GROUP VIII-METAL COMPLEXES USEFUL AS ANTITUMOR AGENTS</title><date>1986-11-01</date><risdate>1986</risdate><abstract>Novel bis[bis(diphenylphosphino)hydrocarbon] and bis[diphenylphosphino-diphenylarsino)hydrcarbon]-group VIII metal compounds of the formula 1 of the formula sheet, whereinD, = D2 = phosphorus or D, = phosphorus and D2 = arsenic;A = (CH2)2 or cis-CH = CH;X, = X2 (both if present) = halo or nitrato or X, + X = peroxo;Y (if present) = halide, nitrate, perchlorate, triflate or tetrahaloferrate (III);n = 0, 1 or 2;M = Fe(II), Fe(III), Co(II), Rh(I), Rh(III), Ir(I), Ir(III), Ni(II) or Pd(II),showing a tumor cell growth-inhibiting activity, novel pharmaceutical compositions containing said compounds and a method for treating tumor cells, sensitive to said compounds.</abstract><edition>4</edition><oa>free_for_read</oa></addata></record> |
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subjects | ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | PROCESS FOR PREPARING PHOSPHINO-HYDROCARBON-GROUP VIII-METAL COMPLEXES USEFUL AS ANTITUMOR AGENTS |
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