PROCESS FOR PREPARING IMIDAZOLIUM SALTS USEFUL AS HYPOGLYCEMIC AGENTS
The invention relates to imidazolium salts which are effective in lowering blood glucose levels in mammals. In particular, there is provided a compound of formula (I) which is useful in lowering blood glucose levels: in which: R is C1-C4 alkyl; R and R , independently, are hydrogen or C1-C4 alkyl; e...
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| creator | TERENCE T.T.YEN SAMUEL JAMES DOMINIANNI |
| description | The invention relates to imidazolium salts which are effective in lowering blood glucose levels in mammals. In particular, there is provided a compound of formula (I) which is useful in lowering blood glucose levels:
in which:
R is C1-C4 alkyl;
R and R , independently, are hydrogen or C1-C4 alkyl;
each R , independently is, -OR , -NR R , C1-C4 alkyl, C1-C4 alkoxy, trifluoromethyl, or C1-C4 alkylthio;
R is hydrogen or -@-R ;
R is hydrogen, C1-C4 alkyl, or -@-R ;
R is hydrogen or C1-C4 alkyl;
each R , independently, is C1-C4 alkyl or phenyl;
Z is oxygen or sulfur;
X is a therapeutically acceptable anion; and
m is 0, 1 or 2. |
| format | Patent |
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in which:
R is C1-C4 alkyl;
R and R , independently, are hydrogen or C1-C4 alkyl;
each R , independently is, -OR , -NR R , C1-C4 alkyl, C1-C4 alkoxy, trifluoromethyl, or C1-C4 alkylthio;
R is hydrogen or -@-R ;
R is hydrogen, C1-C4 alkyl, or -@-R ;
R is hydrogen or C1-C4 alkyl;
each R , independently, is C1-C4 alkyl or phenyl;
Z is oxygen or sulfur;
X is a therapeutically acceptable anion; and
m is 0, 1 or 2.</description><edition>4</edition><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1985</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19851201&DB=EPODOC&CC=PT&NR=81439A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19851201&DB=EPODOC&CC=PT&NR=81439A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>TERENCE T.T.YEN</creatorcontrib><creatorcontrib>SAMUEL JAMES DOMINIANNI</creatorcontrib><title>PROCESS FOR PREPARING IMIDAZOLIUM SALTS USEFUL AS HYPOGLYCEMIC AGENTS</title><description>The invention relates to imidazolium salts which are effective in lowering blood glucose levels in mammals. In particular, there is provided a compound of formula (I) which is useful in lowering blood glucose levels:
in which:
R is C1-C4 alkyl;
R and R , independently, are hydrogen or C1-C4 alkyl;
each R , independently is, -OR , -NR R , C1-C4 alkyl, C1-C4 alkoxy, trifluoromethyl, or C1-C4 alkylthio;
R is hydrogen or -@-R ;
R is hydrogen, C1-C4 alkyl, or -@-R ;
R is hydrogen or C1-C4 alkyl;
each R , independently, is C1-C4 alkyl or phenyl;
Z is oxygen or sulfur;
X is a therapeutically acceptable anion; and
m is 0, 1 or 2.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1985</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZHANCPJ3dg0OVnDzD1IICHINcAzy9HNX8PT1dHGM8vfxDPVVCHb0CQlWCA12dQv1UXAMVvCIDPB394l0dvX1dFZwdHf1CwnmYWBNS8wpTuWF0twMsm6uIc4euqkF-fGpxQWJyal5qSXxASEWhibGlo7GhOQBYMMq7A</recordid><startdate>19851201</startdate><enddate>19851201</enddate><creator>TERENCE T.T.YEN</creator><creator>SAMUEL JAMES DOMINIANNI</creator><scope>EVB</scope></search><sort><creationdate>19851201</creationdate><title>PROCESS FOR PREPARING IMIDAZOLIUM SALTS USEFUL AS HYPOGLYCEMIC AGENTS</title><author>TERENCE T.T.YEN ; SAMUEL JAMES DOMINIANNI</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_PT81439A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1985</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>TERENCE T.T.YEN</creatorcontrib><creatorcontrib>SAMUEL JAMES DOMINIANNI</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>TERENCE T.T.YEN</au><au>SAMUEL JAMES DOMINIANNI</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PROCESS FOR PREPARING IMIDAZOLIUM SALTS USEFUL AS HYPOGLYCEMIC AGENTS</title><date>1985-12-01</date><risdate>1985</risdate><abstract>The invention relates to imidazolium salts which are effective in lowering blood glucose levels in mammals. In particular, there is provided a compound of formula (I) which is useful in lowering blood glucose levels:
in which:
R is C1-C4 alkyl;
R and R , independently, are hydrogen or C1-C4 alkyl;
each R , independently is, -OR , -NR R , C1-C4 alkyl, C1-C4 alkoxy, trifluoromethyl, or C1-C4 alkylthio;
R is hydrogen or -@-R ;
R is hydrogen, C1-C4 alkyl, or -@-R ;
R is hydrogen or C1-C4 alkyl;
each R , independently, is C1-C4 alkyl or phenyl;
Z is oxygen or sulfur;
X is a therapeutically acceptable anion; and
m is 0, 1 or 2.</abstract><edition>4</edition><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | PROCESS FOR PREPARING IMIDAZOLIUM SALTS USEFUL AS HYPOGLYCEMIC AGENTS |
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