PROCESS FOR PREPARING IMIDAZOLIUM SALTS USEFUL AS HYPOGLYCEMIC AGENTS

The invention relates to imidazolium salts which are effective in lowering blood glucose levels in mammals. In particular, there is provided a compound of formula (I) which is useful in lowering blood glucose levels: in which: R is C1-C4 alkyl; R and R , independently, are hydrogen or C1-C4 alkyl; e...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: TERENCE T.T.YEN, SAMUEL JAMES DOMINIANNI
Format: Patent
Sprache:eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The invention relates to imidazolium salts which are effective in lowering blood glucose levels in mammals. In particular, there is provided a compound of formula (I) which is useful in lowering blood glucose levels: in which: R is C1-C4 alkyl; R and R , independently, are hydrogen or C1-C4 alkyl; each R , independently is, -OR , -NR R , C1-C4 alkyl, C1-C4 alkoxy, trifluoromethyl, or C1-C4 alkylthio; R is hydrogen or -@-R ; R is hydrogen, C1-C4 alkyl, or -@-R ; R is hydrogen or C1-C4 alkyl; each R , independently, is C1-C4 alkyl or phenyl; Z is oxygen or sulfur; X is a therapeutically acceptable anion; and m is 0, 1 or 2.