ESFINGOSSOMAS PARA UM FORNECIMENTO DE DROGAS MELHORADO

Liposomal formulations having extended circulation time in vivo and increased drug retention are comprised of sphingomyelin and cholesterol and have an acidic intraliposomal pH. The formulations have enhanced stability and thus are used in methods which provide improved drug delivery and more effect...

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Hauptverfasser:	LAWRENCE D. MAYER, MARCEL B. BALLY, JAMES M. MILLER, PAUL G. TARDI, MURRAY S. WEBB
Format:	Patent
Sprache:	por
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator	LAWRENCE D. MAYER MARCEL B. BALLY JAMES M. MILLER PAUL G. TARDI MURRAY S. WEBB
description	Liposomal formulations having extended circulation time in vivo and increased drug retention are comprised of sphingomyelin and cholesterol and have an acidic intraliposomal pH. The formulations have enhanced stability and thus are used in methods which provide improved drug delivery and more effective treatment. The delivery of lipophilic drugs such as the vinca alkaloids, and particularly vincristine and vinblastine, to tumors is significantly improved.
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subjects	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title	ESFINGOSSOMAS PARA UM FORNECIMENTO DE DROGAS MELHORADO
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