PROTEINA LIGANTE A ATP E ACIDOS NUCLEICOS COM PROPRIEDADE DE HELICASE E DE ATPASE

Nucleic acid binding protein (I) with helicase activity, the mRNA of which (or its translation products) are strongly expressed in presence of leflunomide (II, i.e. 4-(N-(4-trifluoromethylphenyl)-5-methyl-isoxazole)) or compounds with similar activity is new. Also new are: (1) DNA (III) encoding (I)...

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Hauptverfasser: BARTLETT, ROBERT, MUELLNER, STEFAN, KIRSCHBAUM, BERND
Format: Patent
Sprache:por
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Zusammenfassung:Nucleic acid binding protein (I) with helicase activity, the mRNA of which (or its translation products) are strongly expressed in presence of leflunomide (II, i.e. 4-(N-(4-trifluoromethylphenyl)-5-methyl-isoxazole)) or compounds with similar activity is new. Also new are: (1) DNA (III) encoding (I), or parts of it, and sequences that hybridise under stringent conditions with (III); (2) vectors containing (III) or sequences antisense to (III) and (3) host cells containing (III) or the vectors.