PROCESS FOR PREPARING NEW SUBSTITUTED 3-(PARASUBSTITUTED) PHENOXY-1-ALKYLAMINO-PROPANOL-2-S AND OF PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME

PROCESS FOR PREPARING NEW SUBSTITUTED 3-(PARASUBSTITUTED) PHENOXY-1-ALKYLAMINO-PROPANOL-2-S AND OF PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME

Compounds of the formula I wherein R is selected from the group consisting of hydrogen or methyl, m is an integer 0 or 1, whereby when m is 0, R and R are the same and are selected from the group consisting of methoxy, fluoro, bromo, and chloro in 2- and 6-position, whereby when m is 1, R is hydroge...

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Hauptverfasser: BRITT INGER MONICA KAELLSSON, BILL BENJAMIN RUDOLF GUSTAFSSON, ENAR INGEMAR CARLSSON, ANNIE HILLEVI MATTSSON
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Zusammenfassung:Compounds of the formula I wherein R is selected from the group consisting of hydrogen or methyl, m is an integer 0 or 1, whereby when m is 0, R and R are the same and are selected from the group consisting of methoxy, fluoro, bromo, and chloro in 2- and 6-position, whereby when m is 1, R is hydrogen and R is selected from the group consisting of hydrogen, methoxy, ethoxy, acetyl, methyl, hydroxymethyl, cyano, chloro, fluoro, bromo, or hydroxy, or a pharmaceutically acceptable salt thereof, as well as their preparation, pharmaceutical preparations containing the same, and method of treating cardiac failure. The compounds which possess beta-adrenoceptor stimulating activity are intended for treatment of cardiac disease whereby the compounds possess a pronounced inotropic effect.