METHOD FOR THE PREPARATION OF NEW DERIVATES OF THE ACID 2,4,6-TRI-IODO-ISOFTALIC AND X-RAYS CONTRAST PRODUCTS CONTAINING SUCH DERIVATES

Compounds for use in non-ionic X-ray contrasting materials having the formula in which (H0)2-3alkyl is 1,3-dihydroxyisopropyl, 2,3-dihydroxypropyl or 1,3-dihydroxy-2-hydroxymethylisopropyl, R is hydrogen or methyl, and R1 is an alkyl residue with 1 to 5 carbon atoms. These compounds possess high wat...

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Hauptverfasser: ERNEST FELDER, DAVIDE PITRE
Format: Patent
Sprache:eng
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Zusammenfassung:Compounds for use in non-ionic X-ray contrasting materials having the formula in which (H0)2-3alkyl is 1,3-dihydroxyisopropyl, 2,3-dihydroxypropyl or 1,3-dihydroxy-2-hydroxymethylisopropyl, R is hydrogen or methyl, and R1 is an alkyl residue with 1 to 5 carbon atoms. These compounds possess high water-solubility as well as excellent stability against hydrolysis. Methods for preparation and use of the compounds are also disclosed.