PROCEDE DE PREPARATION DE DERIVES DE PYRAZOLIDINE-DIONE APPLICABLES EN THERAPEUTIQUE

Pyrazolidine-dione derivatives of the formula in which R1 and R2 are the same or different and each is hydrogen or alkyl of 1 to 6 carbon atoms, or R1 and R2 together with the nitrogen to which they are attached form a heterocyclic ring which may or may not contain another hetero-atom which can itse...

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1. Verfasser: HENRY NAJER
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Sprache:fre
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Zusammenfassung:Pyrazolidine-dione derivatives of the formula in which R1 and R2 are the same or different and each is hydrogen or alkyl of 1 to 6 carbon atoms, or R1 and R2 together with the nitrogen to which they are attached form a heterocyclic ring which may or may not contain another hetero-atom which can itself carry a substituent, are useful in therapy as inhibitors of platelet aggregation. They may be made from the corresponding unsubstituted pyrazolidine-dione by a Mannich reaction.