HOMODIMERO P40 DA INTERLEUCINA 12

The present invention is directed towards a protein comprising two p40 subunits of interleukin-12 which are associated together, preferably by at least one disulfide bond, having a molecular weight of about 80 kDa. The 80 kDa p40 homodimer acts as an interleukin-12 receptor antagonist. The preferred...

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Bibliographische Detailangaben
Hauptverfasser: JOHN HAKIMI, MAURICE KENT GATELY, PING LING
Format: Patent
Sprache:por
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Zusammenfassung:The present invention is directed towards a protein comprising two p40 subunits of interleukin-12 which are associated together, preferably by at least one disulfide bond, having a molecular weight of about 80 kDa. The 80 kDa p40 homodimer acts as an interleukin-12 receptor antagonist. The preferred p40 subunit is that of SEQ ID NO:1.