HETEROBICYCLOARYL RORC2 INHIBITORS AND METHODS OF USE THEREOF

The present invention provides compounds, pharmaceutical compositions, methods of inhibiting RORy activity and/or reducing the amount of IL-17 in a subject, and methods of treating various medical disorders using such compounds and pharmaceutical compositions.

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Bibliographische Detailangaben
Hauptverfasser:	RAVI G. KURUMBAIL, JAMES RICHARD JR. KIEFER, NEELU KAILA, EDOUARD ZAMARATSKI, ATLI THORARENSEN, LI XING, JAMES ROBERT BLINN, PETER JONES, MARK EDWARD SCHNUTE, ANDREW CHRISTOPHER FLICK, CHRISTOPH WOLFGANG ZAPF, GÖRAN MATTIAS WENNERSTÅL, MARVIN JAY MEYERS, SCOT RICHARD MENTE
Format:	Patent
Sprache:	eng ; por
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides compounds, pharmaceutical compositions, methods of inhibiting RORy activity and/or reducing the amount of IL-17 in a subject, and methods of treating various medical disorders using such compounds and pharmaceutical compositions.