CHEMICAL ENTITIES

Provided are chemical entities selected from compounds of formula (I), wherein R1, R2 and m have meanings given in the description, and pharmaceutically acceptable salts, solvates and stereoisomers thereof, which are inhibitors of ATR and are potentially useful in the treatment of cancer. Further pr...

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Hauptverfasser:	OSCAR FERNÁNDEZ-CAPETILLO RUIZ, LUIS IGNACIO TOLEDO LÁZARO, JOAQUÍN PASTOR FERNÁNDEZ, DAVID ALVARO CEBRIÁN MUÑOZ, SONSOLES RODRÍGUEZ ARÍSTEGUÍ, CARMEN VARELA BUSTO, CARMEN BLANCO APARICIO, MATILDE MURGA COSTA, MARÍA DEL ROSARIO RICO FERREIRA, SONIA MARTÍNEZ GONZÁLEZ
Format:	Patent
Sprache:	eng ; por
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Provided are chemical entities selected from compounds of formula (I), wherein R1, R2 and m have meanings given in the description, and pharmaceutically acceptable salts, solvates and stereoisomers thereof, which are inhibitors of ATR and are potentially useful in the treatment of cancer. Further provided are pharmaceutical compositions of the chemical entities, combination products containing the chemical entities, the use of the compositions as therapeutic agents, and methods of treatment using these compositions.