PROCESS FOR MAKING MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR

PROCESS FOR MAKING MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR

The invention provides a process for the preparation of a compound of Formula 1; comprising coupling a carboxylic acid of Formula 2; with an aniline of Formula 2; in the presence of a coupling agent.

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Bibliographische Detailangaben
Hauptverfasser: MARTIN TRUDEAU, MICHAEL RYAN, BOBBIANA NEUBERT-LANGILLE, GREGOR ZLOKARNIK, PETER D. J. GROOTENHUIS, JOHN DEMATTEI, STEFANIE ROPER, FREDERICK F. VAN GROOR, BRIAN R. KRUEGER, MARTYN C. BOTFIELD, DAHRIKA MILFRED LAO YAP, ADAM R. LOOKER
Format: Patent
Sprache:eng ; por
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The invention provides a process for the preparation of a compound of Formula 1; comprising coupling a carboxylic acid of Formula 2; with an aniline of Formula 2; in the presence of a coupling agent.