NEW CRYSTALLINE FORMS OF THE SODIUM SALT OF (4- {4- [5- ( 6 - TRIFLUOROMETHYL - PYRIDIN- 3 - YLAMINO ) - PYRIDIN- 2 -YL]-PHENYL} - CYCLOHEXYL) -ACETIC ACID

NEW CRYSTALLINE FORMS OF THE SODIUM SALT OF (4- {4- [5- ( 6 - TRIFLUOROMETHYL - PYRIDIN- 3 - YLAMINO ) - PYRIDIN- 2 -YL]-PHENYL} - CYCLOHEXYL) -ACETIC ACID

The present invention relates to novel crystalline forms of (4-{4-[5-(6-Trifluoromethylpyridin-3-ylamino)-pyridin-2-yl]-phenyl}-cyclohexyl)-acetic acid, sodium and their use in the treatment or prevention of a condition or a disorder associated with DGAT1 activity in animals, particularly humans. It...

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Bibliographische Detailangaben
Hauptverfasser: EDWIN BERNARD VILLHAUER, PAUL ALLEN SUTTON, MICHAEL J. GIRGIS, MAHAVIR PRASHAD, JESSICA LIANG
Format: Patent
Sprache:eng ; por
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:The present invention relates to novel crystalline forms of (4-{4-[5-(6-Trifluoromethylpyridin-3-ylamino)-pyridin-2-yl]-phenyl}-cyclohexyl)-acetic acid, sodium and their use in the treatment or prevention of a condition or a disorder associated with DGAT1 activity in animals, particularly humans. It also relates processes for making such novel crystalline forms.