OPTIMISED METHOD FOR OBTAINING ANGIOTENSIN CONVERTING ENZYME INHIBITORY PEPTIDES, INHIBITORY PEPTIDES AND FOOD CONTAINING SAME

The present invention relates to an optimized method for obtaining ACE activity inhibitory peptides wherein it includes the steps of whey ultrafiltration for obtaining a whey concentrate, enzymatic hydrolysis, hydrolysate ultrafiltration and inhibitory peptide separation, which comprises selecting a...

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Hauptverfasser: NATALIA ESTEVEZ TELLE, LORENZO PASTRANA CASTRO, MARIA LUISA RUA RODRIGUEZ, ANGEL PEREIRA RODRIGUEZ, JUAN PABLO FUCIÑOS GONZALEZ, BENIGNO PEREIRA RAMOS
Format: Patent
Sprache:eng ; por
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Zusammenfassung:The present invention relates to an optimized method for obtaining ACE activity inhibitory peptides wherein it includes the steps of whey ultrafiltration for obtaining a whey concentrate, enzymatic hydrolysis, hydrolysate ultrafiltration and inhibitory peptide separation, which comprises selecting and adding a mixture having suitable proportion and amount of two microbial proteases and having complementary action to said whey concentrate for the hydrolysis thereof in order to obtain peptides with an ACE inhibition percentage greater than 70% and an IC 50 index of 30 to 100 µg/ml.