NEW HISTONE DEACETYLASE INHIBITORS BASED SIMULTANEOUSLY ON TRISUBSTITUTED 1H-PYRROLES AND AROMATIC AND HETEROAROMATIC SPACERS

The present invention refers to compounds derived from trisubstituted 1H-pyrrole rings and aromatic rings, which have the following formula (I): as well as to the procedure for their preparation and the use thereof for the treatment of cancer by inhibiting histone deacetylases and the therapeutic us...

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Bibliographische Detailangaben
Hauptverfasser:	DORLETA OTAEGUI ANSA, YOSU ION VARA SALAZAR, ENEKO ALDABA ARÉVALO, AIZPEA ZUBIA OLASCOAGA, FERNANDO PEDRO COSSÍO MORA, MARÍA DEL CARMEN MASDEU MARGALEF, EIDER SAN SEBASTIÁN LARZABAL
Format:	Patent
Sprache:	eng ; por
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention refers to compounds derived from trisubstituted 1H-pyrrole rings and aromatic rings, which have the following formula (I): as well as to the procedure for their preparation and the use thereof for the treatment of cancer by inhibiting histone deacetylases and the therapeutic use of biological processes related to the mentioned inhibition.