AMINOHETEROARYL COMPOUNDS AS PROTEIN KINASE INHIBITORS

Aminopyridine and aminopyrazine compounds of formula (1), compositions including these compounds, and methods of their use are provided. Preferred compounds of formula 1 have activity as protein kinase inhibitors, including as inhibitors of c-MET.

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Bibliographische Detailangaben
Hauptverfasser:	FANG-JIE ZHANG, MITCHELL DAVID NAMBU, JASON LIN, DAVIS G. HARRIS, ALLISON WALTER, MASON ALAN PAIRISH, LEE A. FUNK, JERRY JIALUN MENG, JOANNE JOHNSON, PEI-PEI KUNG, CHRISTOPHER G. NELSON, XIAOYUAN LI, JINGJONG JEAN CUI, JENNIFER ZHANG, DILIP BHUMRALKAR, CATHLEEN ELIZABETH HANAU, IRINY BOTROUS, MICHELLE TRAN-DUBE, LEI JIA, STEPHEN A. KOLODZIEJ, JI YU CHU, HONG SHEN
Format:	Patent
Sprache:	eng ; por
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Aminopyridine and aminopyrazine compounds of formula (1), compositions including these compounds, and methods of their use are provided. Preferred compounds of formula 1 have activity as protein kinase inhibitors, including as inhibitors of c-MET.