OPTIMIZED NON-CANONICAL ZINC FINGER PROTEINS

Disclosed herein are zinc fingers comprising CCHC zinc coordinating residues. Also disclosed are zinc finger proteins and fusion proteins comprising these CCHC zinc fingers as well as polynucleotides encoding these proteins. Methods of using these proteins for gene editing and gene regulations are a...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	NICOLE L. ARNOLD, RYAN C. BLUE, ROBBI J. GARRISON, FYODOR URNOV, JOSEPH F. PETOLINO, SARAH E. WORDEN, QIHUA C. CAI, LISA W. BAKER, JON C. MITCHELL, VIPULA K. SHUKLA, JEFFREY MILLER
Format:	Patent
Sprache:	eng ; por
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Disclosed herein are zinc fingers comprising CCHC zinc coordinating residues. Also disclosed are zinc finger proteins and fusion proteins comprising these CCHC zinc fingers as well as polynucleotides encoding these proteins. Methods of using these proteins for gene editing and gene regulations are also described.