OLIGORIBONUCUCLEOTIDE FOR INHIBITING THE EXPRESSION OF A PREDEFINED GENE

A new method to inhibit the expression of a predetermined target gene in a cell, comprises introducing an oligoribonucleotide with double stranded structure (dsRNA) or a vector coding for the dsRNA into the cell, where a strand of the dsRNA is at least in part complementary to the target gene. ACTIV...

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Bibliographische Detailangaben
Hauptverfasser: ROLAND KREUTZER, STEPHAN LIMMER
Format: Patent
Sprache:eng ; por
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Zusammenfassung:A new method to inhibit the expression of a predetermined target gene in a cell, comprises introducing an oligoribonucleotide with double stranded structure (dsRNA) or a vector coding for the dsRNA into the cell, where a strand of the dsRNA is at least in part complementary to the target gene. ACTIVITY : Antiviral; cytostatic; anti-prion. MECHANISM OF ACTION : Double stranded RNA inhibitor of gene expression.