PREPARATION OF CONTROLLED RELEASE SKELETAL MUSCLE RELAXANT DOSAGE FORMS

The present invention is directed to a method of preparing an extended release pharmaceutical composition comprising cyclobenzaprine, comprising coating inert particles with a cyclobenzaprine-containing a drug layering composition to form IR beads, then coating the IR beads with an extended-release...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: GOPI VENKATESH, JAMES M. CLEVENGER, TIMOTHY GRINSTEAD
Format: Patent
Sprache:eng ; por
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Beschreibung
Zusammenfassung:The present invention is directed to a method of preparing an extended release pharmaceutical composition comprising cyclobenzaprine, comprising coating inert particles with a cyclobenzaprine-containing a drug layering composition to form IR beads, then coating the IR beads with an extended-release coating to form ER beads.