TARGETED BINDING AGENTS DIRECTED TO PDGFR-ALPHA AND USES THEREOF

TARGETED BINDING AGENTS DIRECTED TO PDGFR-ALPHA AND USES THEREOF

Targeted binding agents directed to the antigen PDGFR-alpha and uses of such agents are disclosed herein. More specifically the invention relates to fully human monoclonal antibodies directed to the antigen PDGFR-alpha and uses of these antibodies. Aspects of the invention also relate to hybridomas...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: GADI GAZIT-BORNSTEIN, IAN FOLTZ, XIAODONG YANG, NAOMI LAING, JASPAL SINGH KANG, SUSAN ANN CARTLIDGE, DAVID CHARLES BLAKEY, LAURA TAYLOR
Format: Patent
Sprache:eng ; por
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:Targeted binding agents directed to the antigen PDGFR-alpha and uses of such agents are disclosed herein. More specifically the invention relates to fully human monoclonal antibodies directed to the antigen PDGFR-alpha and uses of these antibodies. Aspects of the invention also relate to hybridomas or other cell lines expressing such antibodies. The described targeted binding agents and antibodies are useful as diagnostics and for the treatment of diseases associated with the activity and/or overexpression of PDGFR-alpha.