ANTI-MYOSTATIN ANTIBODIES

ANTI-MYOSTATIN ANTIBODIES

Anti-myostatin antibodies are identified that are characterized as having high affinity and may be chimeric, humanized or fully human antibodies, immunoconjugates of the antibodies or antigen-binding fragments thereof. The antibodies of the invention are useful for increasing muscle mass, increasing...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: JULIAN DAVIES, RONG WANG, LINDA O. O'BRYAN (NEE TOBIAS), BRYAN EDWARD JONES, PAMELA JEAN MITCHELL, ANDREW IHOR KORYTKO, ROSAMUND CAROL SMITH
Format: Patent
Sprache:eng ; por
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Anti-myostatin antibodies are identified that are characterized as having high affinity and may be chimeric, humanized or fully human antibodies, immunoconjugates of the antibodies or antigen-binding fragments thereof. The antibodies of the invention are useful for increasing muscle mass, increasing bone density, or for the treatment of various disorders in mammalian and avian species.