5-LIPOXYGENASE-ACTIVATING PROTEIN (FLAP) INHIBITORS

5-LIPOXYGENASE-ACTIVATING PROTEIN (FLAP) INHIBITORS

Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of 5-lipoxygenase-activating protein (FLAP). Also described herein are methods of using such FLAP modulators, alone and in combination with other compounds, for treating respiratory,...

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Bibliographische Detailangaben
Hauptverfasser: JASMINE ELEANOR ZUNIC, NICHOLAS SIMON STOCK, JOHN HOWARD HUTCHINSON, JEFFREY ROGER ROPPE, MUSTAPHA HADDACH, BRIAN ANDREW STEARNS, JILLIAN F. EVANS, YIWEI LI, PETPIBOON PEPPI PRASIT, JEANNIE M. ARRUDA, MARK MORAN
Format: Patent
Sprache:eng ; por
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of 5-lipoxygenase-activating protein (FLAP). Also described herein are methods of using such FLAP modulators, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other leukotriene-dependent or leukotriene mediated conditions or diseases.