PHARMACEUTICAL COMPOSITION COMPRISING GRANULAR PANTOPRAZOLE

PHARMACEUTICAL COMPOSITION COMPRISING GRANULAR PANTOPRAZOLE

Pharmaceutical composition comprising pantoprazole as the active ingredient. The pantoprazole is present in the form of particles having an average particle size within the range of 60 ¼m to 250 ¼m. Pantoprazole having an average particle size within the range of 60 ¼m to 250 ¼m is prepared by a pro...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: FRANC VRECER, MARJANCA BREZNIK, ANDREJ FERLAN, ANDREJKA KRAMAR, LIDIA CERNOSA, URSKA TURK, GREGOR RITLOP
Format: Patent
Sprache:eng ; por
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:Pharmaceutical composition comprising pantoprazole as the active ingredient. The pantoprazole is present in the form of particles having an average particle size within the range of 60 ¼m to 250 ¼m. Pantoprazole having an average particle size within the range of 60 ¼m to 250 ¼m is prepared by a process comprising the steps of wetting pantoprazole with water having a pH of 10 to 12 in a high shear mixer, passing the wet pantoprazole through a sieve having a mesh size of 0.8 to 2 mm, and drying the mass in a fluid bed dryer.