6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO [D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS
The present invention provides 6-substituted 2,3,4,5-tetrahydro-1H-benzo[d]azepines of Formula I as selective 5-HT 2C receptor agonists for the treatment of 5-HT 2C associated disorders including obesity, obsessive/compulsive disorder, depression, and anxiety: where: R 6 is -S-L-R 15 and other subst...
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| creator | MICHAEL JOHN RODRIGUEZ SARAH LYNNE HELLMAN MARIA ANGELES MARTINEZ-GRAU DEYI ZHANG AJAY SINGH ANDREW CAERWYN WILLIAMS MATTHEW ROBERT REINHARD JOHN GORDON ALLEN MICHAEL WADE TIDWELL CHRISTOPHER STEPHEN SIEDEM KARIN BRINER WAI-MAN LEE FRANTZ VICTOR ROGER RYAN ROTHHAAR CHRISTOPHER STANLEY GALKA MICHAEL PHILIP COHEN |
| description | The present invention provides 6-substituted 2,3,4,5-tetrahydro-1H-benzo[d]azepines of Formula I as selective 5-HT 2C receptor agonists for the treatment of 5-HT 2C associated disorders including obesity, obsessive/compulsive disorder, depression, and anxiety:
where:
R 6 is -S-L-R 15
and other substituents are as defined in the specification. |
| format | Patent |
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where:
R 6 is -S-L-R 15
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where:
R 6 is -S-L-R 15
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where:
R 6 is -S-L-R 15
and other substituents are as defined in the specification.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | 6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO [D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS |
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