MACROCYCLIC CARBOXYLIC ACID AND ACYLSULFONAMIDE COMPOUND AS INHIBITOR OF HCV REPLICATION
The present application provides compounds of the general formulas I-IX as defined herein, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The present application further provides treatment methods, including methods of treating a hepatitis C virus infe...
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| creator | LAWRENCE M. BLATT YUTONG JIANG MACHENDER R. DURU GEORGE ANDREW DOHERTY STEVEN WADE ANDREWS JOHN ANTHONY JOSEY KEVIN RONALD CONDROSKI SCOTT D. SEIWERT APRIL LAYNE KENNEDY STEVEN MARK WENGLOWSKY BENJAMIN T. WOODARD PETER JOHN STENGEL |
| description | The present application provides compounds of the general formulas I-IX as defined herein, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The present application further provides treatment methods, including methods of treating a hepatitis C virus infection and methods of treating liver fibrosis, the methods generally involving administering to an individual in need thereof an effective amount of a subject compound or composition. |
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The present application further provides treatment methods, including methods of treating a hepatitis C virus infection and methods of treating liver fibrosis, the methods generally involving administering to an individual in need thereof an effective amount of a subject compound or composition.</description><language>eng ; por</language><subject>CHEMISTRY ; COMPOSITIONS BASED THEREON ; DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; ORGANIC MACROMOLECULAR COMPOUNDS ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; THEIR PREPARATION OR CHEMICAL WORKING-UP</subject><creationdate>2013</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20130221&DB=EPODOC&CC=PT&NR=1680137E$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20130221&DB=EPODOC&CC=PT&NR=1680137E$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LAWRENCE M. 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DURU</creatorcontrib><creatorcontrib>GEORGE ANDREW DOHERTY</creatorcontrib><creatorcontrib>STEVEN WADE ANDREWS</creatorcontrib><creatorcontrib>JOHN ANTHONY JOSEY</creatorcontrib><creatorcontrib>KEVIN RONALD CONDROSKI</creatorcontrib><creatorcontrib>SCOTT D. SEIWERT</creatorcontrib><creatorcontrib>APRIL LAYNE KENNEDY</creatorcontrib><creatorcontrib>STEVEN MARK WENGLOWSKY</creatorcontrib><creatorcontrib>BENJAMIN T. WOODARD</creatorcontrib><creatorcontrib>PETER JOHN STENGEL</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>LAWRENCE M. BLATT</au><au>YUTONG JIANG</au><au>MACHENDER R. DURU</au><au>GEORGE ANDREW DOHERTY</au><au>STEVEN WADE ANDREWS</au><au>JOHN ANTHONY JOSEY</au><au>KEVIN RONALD CONDROSKI</au><au>SCOTT D. SEIWERT</au><au>APRIL LAYNE KENNEDY</au><au>STEVEN MARK WENGLOWSKY</au><au>BENJAMIN T. WOODARD</au><au>PETER JOHN STENGEL</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>MACROCYCLIC CARBOXYLIC ACID AND ACYLSULFONAMIDE COMPOUND AS INHIBITOR OF HCV REPLICATION</title><date>2013-02-21</date><risdate>2013</risdate><abstract>The present application provides compounds of the general formulas I-IX as defined herein, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The present application further provides treatment methods, including methods of treating a hepatitis C virus infection and methods of treating liver fibrosis, the methods generally involving administering to an individual in need thereof an effective amount of a subject compound or composition.</abstract><oa>free_for_read</oa></addata></record> |
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| language | eng ; por |
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| subjects | CHEMISTRY COMPOSITIONS BASED THEREON DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY ORGANIC MACROMOLECULAR COMPOUNDS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES THEIR PREPARATION OR CHEMICAL WORKING-UP |
| title | MACROCYCLIC CARBOXYLIC ACID AND ACYLSULFONAMIDE COMPOUND AS INHIBITOR OF HCV REPLICATION |
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