MACROCYCLIC CARBOXYLIC ACID AND ACYLSULFONAMIDE COMPOUND AS INHIBITOR OF HCV REPLICATION

The present application provides compounds of the general formulas I-IX as defined herein, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The present application further provides treatment methods, including methods of treating a hepatitis C virus infe...

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Bibliographische Detailangaben
Hauptverfasser:	LAWRENCE M. BLATT, YUTONG JIANG, MACHENDER R. DURU, GEORGE ANDREW DOHERTY, STEVEN WADE ANDREWS, JOHN ANTHONY JOSEY, KEVIN RONALD CONDROSKI, SCOTT D. SEIWERT, APRIL LAYNE KENNEDY, STEVEN MARK WENGLOWSKY, BENJAMIN T. WOODARD, PETER JOHN STENGEL
Format:	Patent
Sprache:	eng ; por
Schlagworte:	CHEMISTRY COMPOSITIONS BASED THEREON DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY ORGANIC MACROMOLECULAR COMPOUNDS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES THEIR PREPARATION OR CHEMICAL WORKING-UP
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Beschreibung
Zusammenfassung:	The present application provides compounds of the general formulas I-IX as defined herein, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The present application further provides treatment methods, including methods of treating a hepatitis C virus infection and methods of treating liver fibrosis, the methods generally involving administering to an individual in need thereof an effective amount of a subject compound or composition.