CRYSTALLISATION OF SOLID FORMS OF CLOPIDOGREL ADDITION SALTS

CRYSTALLISATION OF SOLID FORMS OF CLOPIDOGREL ADDITION SALTS

The invention relates to a process for the preparation of form 1 and form 2 of clopidogrel hydrogen sulfate, a process for the preparation of amorphous clopidogrel hydrogen sulfate, the 2-propylsulfate of clopidogrel, the perchlorate of clopidogrel and methods for the preparation of these compounds.

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Bibliographische Detailangaben
Hauptverfasser: IGOR SIMONIC, MARIJA GRCMAN, MILOS RUZIC, ANICA PECAVAR, BERTA KOTAR-JORDAN, ROK ZUPET
Format: Patent
Sprache:eng ; por
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The invention relates to a process for the preparation of form 1 and form 2 of clopidogrel hydrogen sulfate, a process for the preparation of amorphous clopidogrel hydrogen sulfate, the 2-propylsulfate of clopidogrel, the perchlorate of clopidogrel and methods for the preparation of these compounds.