MELT EXTRUSION OF SPHERICAL MULTIPARTICULATES

MELT EXTRUSION OF SPHERICAL MULTIPARTICULATES

The invention relates to a process for preparing a controlled release pharmaceutical extrudate using a melt extruder, wherein the melt extruder comprises a die-head supporting a die-plate in which orifices are located, and a cutter adjacent to the die-head, and wherein the cutter cuts the extruded m...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: DEREK ALLAN PRATER, VINCENZO MARTINELLI, MALCOLM WALDEN, STEVE WHITELOCK, GEOFFREY GERARD HAYES, HASSAN MOHAMMAD, HARJIT TAMBER
Format: Patent
Sprache:eng ; por
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The invention relates to a process for preparing a controlled release pharmaceutical extrudate using a melt extruder, wherein the melt extruder comprises a die-head supporting a die-plate in which orifices are located, and a cutter adjacent to the die-head, and wherein the cutter cuts the extruded mix as it emerges under pressure and still molten or softened from the orifices of the die-plate.