PROCESS FOR DEHYDROGENATION OF AZAANDROSTANE COMPOUNDS

The invention relates to a process for the production of compounds of general formula (I), wherein R1 is a -NH-tert-butyl group or a 4-methyl-piperidino group, by bioconversion of compounds of general formula (II), wherein R1 is as described above, using a biocatalyst having steroid-Delta -dehydroge...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: MONIKA HERINE BERTA, GABOR HANTOS, ISTVAN BARTHO, TAMAS DEVENYI, KATALIN OLASZ, AGNES RAZSO PECSNE
Format: Patent
Sprache:eng ; por
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Beschreibung
Zusammenfassung:The invention relates to a process for the production of compounds of general formula (I), wherein R1 is a -NH-tert-butyl group or a 4-methyl-piperidino group, by bioconversion of compounds of general formula (II), wherein R1 is as described above, using a biocatalyst having steroid-Delta -dehydrogenase enzyme activity, wherein the activity of the enzyme needed for the bioconversion is produced by induction.