USE OF MUTATED VEGF FOR ANTIANGIOGENIC THERAPY

The invention relates to the application of oligonucleotide and polypeptide sequences of molecules belonging to the vascular permeability factor (VPF) family, their receptors and co-receptors and to their modifications in active immunotherapy against pathological entities whose course is associated...

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Hauptverfasser:	OMAR LOPEZ OCEJO, DANIA MARCIA VAZQUEZ BLOMQUIST, LUIS ENRIQUE CALLE FERNANDEZ MOLINA, BORIS ERNESTO ACEVEDO CASTRO, MONICA BEQUET ROMERO, JORGE VICTOR GAVILONDO COWLEY, ALEXIS MUSACHIO LASA, GALBAN RODRIGUEZ, ERNESTO, RICARDO DE LA CARIDAD SILVA RODRIGUEZ
Format:	Patent
Sprache:	eng ; por
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention relates to the application of oligonucleotide and polypeptide sequences of molecules belonging to the vascular permeability factor (VPF) family, their receptors and co-receptors and to their modifications in active immunotherapy against pathological entities whose course is associated with an increase in vasculature. Said procedures can be used, inter alia, in monotherapy or combined therapy for the treatment of cancer and its metastasis, acute and chronic inflammatory processes, infectious diseases, autoimmune diseases, diabetic and infant retinopathy, rejection of transplanted organs, macular degeneration, neovascular glaucoma, hemangioma and angiofibroma.