N, N`-DIMETHYLATED N-CONFUSED PORPHYRINS

N, N`-DIMETHYLATED N-CONFUSED PORPHYRINS

A series of N,N'-dimethylated N-confused porphyrin salts were synthesized through methylation of N-confused porphyrins using MeI in the presence of Na2CO3. These compounds have an intense absorption around 790 nm. It has also been shown that N,N'-dimethylated N-confused porphyrin salts can...

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Hauptverfasser: ZIWEI XIAO, DAVID H. DOLPHIN
Format: Patent
Sprache:eng ; por
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:A series of N,N'-dimethylated N-confused porphyrin salts were synthesized through methylation of N-confused porphyrins using MeI in the presence of Na2CO3. These compounds have an intense absorption around 790 nm. It has also been shown that N,N'-dimethylated N-confused porphyrin salts can generate singlet oxygen when irradiated. They are, thus, potential sensitizers for PDT.