DERIVADOS DE FENOL SUBSTITUIDOS OU SEUS SAIS COMO INIBIDORES DO FACTOR X DE COAGULACAO

DERIVADOS DE FENOL SUBSTITUIDOS OU SEUS SAIS COMO INIBIDORES DO FACTOR X DE COAGULACAO

There are provided compounds having an anticoagulant action on the basis of inhibition of activated blood coagulation factor X and being useful as anticoagulants or preventive/therapeutic agents for diseases induced by thrombosis or embolism. Effective ingredients are the compounds such as 4'-b...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: KADOKURA, TAKESHI, FUKUSHI HIRAYAMA, KEIZO SUGASAWA, TSUKASA ISHIHARA, TAKESHI SHIGENAGA, YUJI KOGA
Format: Patent
Sprache:por
Schlagworte:
CHEMISTRY
DERIVATIVES THEREOF
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SUGARS
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Beschreibung
Zusammenfassung:There are provided compounds having an anticoagulant action on the basis of inhibition of activated blood coagulation factor X and being useful as anticoagulants or preventive/therapeutic agents for diseases induced by thrombosis or embolism. Effective ingredients are the compounds such as 4'-bromo-2'-Ä(5-chloro-2-pyridyl)carbamoyl)-6- beta -D-galactopyranosyloxy-1-isopropylpiperidine-4-carboxanilide, 2'-(2-acetamido-2-deoxy- beta -D-glucopyranosyloxy)-4'-bromo-6'-Ä(5-chloro-2-pyridyl)carbamoylÜ-1-is opropylpiperidine-4-carboxanilide, etc. or salts thereof.